https://ogma.newcastle.edu.au/vital/access/ /manager/Index en-au 5 Optimization of commercial microwave assisted-extraction conditions for recovery of phenolics from lemon-scented tee tree (Leptospermum petersonii) and comparison with other extraction techniques https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:46060 0.05). Thus, soaking is not required for the ETHOS X extraction of polyphenols from LSTT leaves. RSM was successfully applied to explore the impact of ETHOS X extraction conditions and optimize the extraction conditions. Radiation time significantly affects the recovery yield of phenolics (p < 0.05) positively, whereas irradiation power and sample to solvent ratio adversely influenced the extraction yields of phenolics. The optimal ETHOS X extraction conditions were: radiation time of 60 min, irradiation power of 600 W, and sample to solvent ratio of 2 g/100 mL. Under these conditions, 119.21 ± 7.09 mg of phenolic, 85.31 ± 4.55 mg of flavonoids, and 137.51 ± 12.52 mg of proanthocyanidins can be extracted from a gram of dried LSTT leaves. In comparison with UAE and SWB, ETHOS X is not more effective for the extraction of phenolics than UAE and SWB. However, this technique can save half of the solvent volume compared to UAE and SWB techniques.]]> Thu 10 Nov 2022 11:28:04 AEDT ]]> Resveratrol restores uterine contractions during hypoxia by blockade of ATP-sensitive potassium channels https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:34698 75% of its contraction capability. The effects of resveratrol on uterine contractions under hypoxia were attenuated by tetraethylammonium (10 mM) and almost abolished by glibenclamide (10 µM). Our results show regenerative and protective effects of resveratrol in non-pregnant murine uteri under hypoxia and describes for the first time that these effects are mediated by blockade of ATP-sensitive potassium channels.]]> Fri 12 Apr 2019 15:45:10 AEST ]]>